In SCARLET NEXUS, a strange life-form called “Others” appeared from the sky and began to prey on the brains of living creatures on the earth – including humans. In order to fight this new kind of enemy, the “Other Suppression Force” (OSF) was created in the city where brain power has been developed, called New Himuka. The OSF is composed of the only people able to exterminate the Others, blessed with exceedingly powerful “brain power” and considered as true heroes by the population.

Every year, more and more recruits are joining the ranks of the OSF to take part to the endless battle between humanity and the Others.